For people with a common genetic variation, researchers have discovered
signs of the possible onset of Alzheimer's before a patient would be
clinically diagnosed by a doctor.
In people with the ApoE4 gene variation, one previously implicated as
affecting the likelihood of Alzheimer's, researchers have been able to
pinpoint some signs of memory loss beginning in the person's mid- to
late-50s -- without the patient having full-blown Alzheimer's disease or
"[One could argue] we really captured for the first time the onset of
Alzheimer's disease," explained Dr. Richard Caselli, a neurologist at the
Mayo Clinic in Scottsdale, Ariz.
"What's passing as normal aging itself correlates with the most common
genetic risk factor for Alzheimer's disease," he said, adding that the
symptoms are noticeable in a clinical setting, but not in everyday life.
"It's not the sort of thing that you can look at somebody or they can look
at themselves and know."
Researchers caution that when in interpreting the findings, one should
keep in mind that people who had shown some memory loss were still
functioning normally and having the gene did not impair anyone at an
The complete article may be read at the URL above.
Bushell, R. & Sheldon, P. (eds),
Wellness and Tourism: Mind, Body, Spirit,
Place, New York: Cognizant Communication Books.
Wellness Tourism: Bibliographic and Webliographic Essay
David P. Dillard